Xeroderma pigmentosum is a genodermatosis characterized by extreme sun sensitivity, photophobia, freckly hyperpigmentation, atrophy, telangiectases, keratoses and finally malignant degeneration of the skin.
It is rare and probably inherited as a recessive trait. Photosensitive cutaneous symptoms developed in complication with squamous cell ca is presented.
A 20-year-old male were studied.
Routine laboratory examinations were within normal limits including hemogram, urinalysis, blood urea nitrogen, serum creatinine, liver function tests (including buomsulphalaein excretion), and serum electrolytes, chest X-Rap.
The histopathological picture showed characteristic xeroderma pigmentosum and squamous cell ca.
Clinical, histopathological and biochemical features of this disease are also discussed.
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